Atrial tachyarrhythmia burden modelling by some electrophysiological parameters in pacemaker-recipient patients with Brady–Tachy syndrome
| Autor: | Donato Melissano, Paolo Azzolini, Alberto Scaccia, A. Puglisi, Vito De Giorgi, Giuseppe Critelli, Giovanni B. Del Giudice, Gianfranco Ibba |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Premature atrial contraction Standard deviation law.invention law Tachycardia Physiology (medical) Internal medicine Linear regression Bradycardia medicine Humans Atrium (heart) Atrial tachycardia Aged Atrial Premature Complexes business.industry P wave Cardiac Pacing Artificial Syndrome medicine.disease medicine.anatomical_structure Data Interpretation Statistical Anesthesia Cardiology Artificial cardiac pacemaker Female medicine.symptom Cardiology and Cardiovascular Medicine business Algorithms |
| Zdroj: | EP Europace. 8:474-481 |
| ISSN: | 1532-2092 1099-5129 |
| DOI: | 10.1093/europace/eul065 |
| Popis: | (1) To correlate atrial tachyarrhythmia (AT) burden of pacemaker-recipient Brady-Tachy syndrome (BTS) patients with a number of diagnostics-derived parameters after 1 month of DDD pacing; (2) to asses whether the activation of atrial overdrive or conventional rate-responsive pacing may affect relevant variables and their correlation.After 1 month of DDD pacing, rate-responsive function or persistent atrial overdrive was randomly activated for 3 months, in 92 BTS patients. Some pacemaker diagnostics parameters collected at 1- and 4-month follow-ups were included in multiple linear regression models, whose dependent variable was the Log transformation of AT burden and compared. With 1-month data, the only variables significantly correlating with Log AT burden were average (with a regression coefficient estimate of -0.07, P=0.02) and standard deviation (0.10, P=0.007) of atrial rate, mean premature atrial contraction (PAC) coupling interval (CI) (-0.005, P=0.001), frequency of PACs with CI500 ms (1.30, P10(-6)). Atrial pacing percentage (APP) and ventricular pacing percentage (VPP), PACs with CI500 ms did not significantly correlate. Four-month data largely confirmed these results, except that in DDDR atrial rate average and standard deviation no longer correlated. Overdrive significantly increased APP and reduced PACs with CI500 ms.AT burden showed significant dependence in DDD and during overdrive on atrial rate average and standard deviation. Highly premature PACs always significantly correlated with AT burden. Though increasing APP, which unexpectedly never correlated, overdrive could only reduce less premature PACs. |
| Databáze: | OpenAIRE |
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