Prevalence and clinical characteristics of cortical superficial siderosis in patients with acute stroke

Autor: Satoshi Suda, Takahiro Ouchi, Kentaro Suzuki, Yuki Sakamoto, Seiji Okubo, Junya Aoki, Chikako Nito, Masahiro Mishina, Shizuka Suzuki, Kazumi Kimura, Yasuhiro Nishiyama, Takashi Shimoyama, Masafumi Arakawa
Rok vydání: 2017
Předmět:
Zdroj: Journal of Neurology. 264:2413-2419
ISSN: 1432-1459
0340-5354
DOI: 10.1007/s00415-017-8646-1
Popis: Cortical superficial siderosis (cSS) is a pathologic and radiologic diagnosis of hemosiderin deposition in subpial brain layers. However, cSS has not been fully studied in patients with acute stroke. Here, we investigated the prevalence of cSS in patients with acute stroke and analyzed the relationship between cSS and different clinical and neuroimaging characteristics. From September 2014 through June 2016, consecutive patients with acute stroke who were admitted to our department were retrospectively investigated. We analyzed the prevalence of cSS and the associations between cSS and risk factors, the topographic distribution of cerebral microbleeds (CMBs), and the severity of white matter lesions (WMLs). In total, 739 patients (589 patients with ischemic stroke/transient ischemic stroke [IS/TIA] and 150 with intracerebral hemorrhage [ICH]; mean age, 71.4 years) were enrolled. We identified cSS in six (1.0%) patients with IS/TIA and seven (4.7%) patients with ICH. The presence of cSS was associated with ICH (P
Databáze: OpenAIRE