Graphene Oxide-Based Nanocomposites Decorated with Silver Nanoparticles as an Antibacterial Agent
| Autor: | Grzegorz Gielerak, Natalia Kurantowicz, André Chwalibog, Anna Jung, Bartosz Woźniak, Artur Małolepszy, Maciej Łojkowski, Leszek Stobinski, Joanna Biernat, Witold Łojkowski, Henryk Jaremek, Marta Mazurkiewicz-Pawlicka, Jacek Wojnarowicz, Sławomir Jaworski, Ewa Sawosz, Mateusz Wierzbicki |
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| Rok vydání: | 2017 |
| Předmět: |
Materials science
Nanochemistry Nanoparticle 02 engineering and technology 010402 general chemistry Cell morphology 01 natural sciences Silver nanoparticle lcsh:TA401-492 General Materials Science Antibacterial agent Graphene oxide Nanocomposite biology Nano Express 021001 nanoscience & nanotechnology Condensed Matter Physics biology.organism_classification Antimicrobial 0104 chemical sciences Antimicrobial properties lcsh:Materials of engineering and construction. Mechanics of materials Silver nanoparticles 0210 nano-technology Bacteria Nuclear chemistry |
| Zdroj: | Nanoscale Research Letters Nanoscale Research Letters, Vol 13, Iss 1, Pp 1-17 (2018) |
| ISSN: | 1931-7573 |
| Popis: | One of the most promising methods against drug-resistant bacteria can be surface-modified materials with biocidal nanoparticles and nanocomposites. Herein, we present a nanocomposite with silver nanoparticles (Ag-NPs) on the surface of graphene oxide (GO) as a novel multifunctional antibacterial and antifungal material. Ultrasonic technologies have been used as an effective method of coating polyurethane foils. Toxicity on gram-negative bacteria (Escherichia coli), gram-positive bacteria (Staphylococcus aureus and Staphylococcus epidermidis), and pathogenic yeast (Candida albicans) was evaluated by analysis of cell morphology, assessment of cell viability using the PrestoBlue assay, analysis of cell membrane integrity using the lactate dehydrogenase assay, and reactive oxygen species production. Compared to Ag-NPs and GO, which have been widely used as antibacterial agents, our nanocomposite shows much higher antimicrobial efficiency toward bacteria and yeast cells. |
| Databáze: | OpenAIRE |
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