A case of esophageal squamous cell carcinoma with positive HPV 11
| Autor: | José Velosa, Catarina L. Vieira, Joao C. Lopes |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Esophageal Neoplasms medicine.medical_treatment Gastroenterology Esophageal stent Internal medicine medicine Carcinoma Humans Esophagus Hepatology medicine.diagnostic_test business.industry Human papillomavirus 11 Middle Aged medicine.disease Dysphagia Endoscopy Stenosis medicine.anatomical_structure Esophagectomy Dysplasia Carcinoma Squamous Cell Esophageal Squamous Cell Carcinoma medicine.symptom business |
| Zdroj: | Gastroenterologia y hepatologia. 36(5) |
| ISSN: | 0210-5705 |
| Popis: | HPV (human pappiloma virus) infection is an etiologic risk factor for esophageal carcinoma with several studies supporting its carcinogenic role. The main strains are HPV16 and 18 and the less frequent strains 11, 6, 31 and 36. We report the case of a 58 year old male, smoker, admitted to our hospital for progressive dysphagia. Previous endoscopies and biopsies were compatible with a hyperkeratotic esophagus, negative for dysplasia. Second endoscopy showed a hyperkeratotic, verrucous, esophagus with two circumferential stenosis which were dilated with TTS (Through the Scope) balloon. Biopsies revealed multiple squamous cell abnormalities, negative for dysplasia and positive for HPV 11. Symptoms recurred, and he was submitted to another upper gastrointestinal endoscopy with dilation of the stenosis and esophageal stent placement. Two months later, esophagectomy was performed, and the histopathological analysis revealed a squamous cell carcinoma of the esophagus (T2, N0, M0, G1). The patient died after surgery due to acute respiratory distress syndrome. |
| Databáze: | OpenAIRE |
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