Purification, molecular docking and in vivo analyses of novel angiotensin-converting enzyme inhibitory peptides from protein hydrolysate of moth bean (Vigna aconitifolia (Jacq.) Màrechal) seeds

Autor:	Amita Bhadkaria, Dakshita Tanaji Narvekar, D.P. Nagar, Sangeeta Pilkwal Sah, Nidhi Srivastava, Sameer Suresh Bhagyawant
Rok vydání:	2022
Předmět:	Structural Biology General Medicine Molecular Biology Biochemistry
Zdroj:	International journal of biological macromolecules.
ISSN:	1879-0003
Popis:	The moth bean is a high-protein legume food. This study aims to produce, screen, and identify natural ACE-I inhibitory peptides derived from moth bean seed protein hydrolysates. The extracted protein was hydrolysed using alcalase, chymotrypsin, flavourzyme, papain, pepsin and trypsin respectively. Alcalase achieved the greatest degree of hydrolysis and ACE inhibition. The highest ACE-I inhibitory activity was exhibited by the peptide with the lowest molecular weight i.e.3 kDa (IC
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c1f89cc6247e0caeeb0e8061fd1d92 https://pubmed.ncbi.nlm.nih.gov/36610577 Zobrazit plný text záznamu Full Text from ScienceDirect