| Autor: |
Lily Yeh Jan, Yoshihiro Kubo, Colin G. Nichols, Takashi Miki, David E. Clapham, Henry Sackin, Atsushi Inanobe, Paul A. Slesinger, John P. Adelman, Andreas Karschin, Stephen J. Tucker, Yoshihisa Kurachi, Michel Lazdunski, Susumu Seino, Lawrence G. Palmer, Carol A. Vandenberg, Wade L. Pearson, Hiroshi Hibino |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
IUPHAR/BPS Guide to Pharmacology CITE, vol 2019, iss 4 |
| ISSN: |
2633-1020 |
| DOI: |
10.2218/gtopdb/f74/2019.4 |
| Popis: |
The 2TM domain family of K channels are also known as the inward-rectifier K channel family. This family includes the strong inward-rectifier K channels (Kir2.x) that are constitutively active, the G-protein-activated inward-rectifier K channels (Kir3.x) and the ATP-sensitive K channels (Kir6.x, which combine with sulphonylurea receptors (SUR1-3)). The pore-forming α subunits form tetramers, and heteromeric channels may be formed within subfamilies (e.g. Kir3.2 with Kir3.3). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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