LBBAP in patients with normal intrinsic QRS duration: Electrical and mechanical characteristics

Autor:	Rongfang Lan, Ning Zhang, Xinyue Xu, Xiang Wu, Wei Xu, Shao-Xian Wang, Jia Zheng, Yuan Gao, Jian Bai, Tianqi Wang
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Male medicine.medical_specialty potential Bundle-Branch Block 030204 cardiovascular system & hematology electrocardiogram 03 medical and health sciences Electrocardiography 0302 clinical medicine Heart Conduction System Internal medicine Left bundle branch medicine Devices Humans In patient 030212 general & internal medicine Lead (electronics) Aged business.industry Cardiac Pacing Artificial Peak systolic strain General Medicine medicine.anatomical_structure Ventricular activation Ventricle Echocardiography Cardiology left bundle branch Female Cardiology and Cardiovascular Medicine Qrs axis business Intrinsic QRS Duration
Zdroj:	Pacing and Clinical Electrophysiology
ISSN:	1540-8159 0147-8389
Popis:	Background Left bundle branch area pacing (LBBAP) is an innovative pacing technology, which needs further study. Methods 70 LBBAP patients with intrinsic QRS duration (QRSd) less than 120 ms were consecutively enrolled in our center. According to whether the left bundle branch potential (LBBp) was recorded or not, the patients were divided into the potential positive group (LBBAP+) and the potential negative group (LBBAP-). Electrocardiographic and echocardiographic parameters were used to evaluate electrical and mechanical characteristics. Lead parameters and complications were followed up. Results There were 52 patients in LBBAP+ and 18 patients in LBBAP-. The QRSd and the left ventricular activation time (LVAT) were wider after LBBAP. QRSd showed no significant difference between LBBAP+ and LBBAP-. LVAT was significantly shorter in LBBAP+ than in LBBAP-. Frontal QRS axis shifted leftward and the V1 morphologies changed after LBBAP. QRS axis and V1 morphologies showed no significant differences between two groups. Paced R-wave transition moved forward compared with intrinsic R-wave transition in both groups. Peak systolic strain of left ventricle (LVPSS) increased and peak systolic dispersion of left ventricle (LVPSD) did not change significantly after LBBAP. Systolic and diastolic function as well as mechanical synchronism had no significant differences between two groups. LBBAP had great pacing parameters. Conclusion LBBAP changes electrical and mechanical characteristics and has good safety in patients with normal intrinsic QRSd. LBBAP+ and LBBAP- show no significant differences in mechanical synchronization and interventricular electrical synchronization. The LBBAP+ shows better left ventricular electrical synchronicity. This article is protected by copyright. All rights reserved.
Databáze:	OpenAIRE
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