Root-Secreted Coumarins and the Microbiota Interact to Improve Iron Nutrition in Arabidopsis
| Autor: | Ruben Garrido-Oter, Stanislav Kopriva, Elizabeth S. Sattely, Adamo Domenico Rombola, Paul Schulze-Lefert, Yulong Niu, Mathias J. Voges, Masayoshi Hashimoto, Christopher J. Harbort, Rui Guan, Haruhiko Inoue |
|---|---|
| Přispěvatelé: | Harbort C.J., Hashimoto M., Inoue H., Niu Y., Guan R., Rombola A.D., Kopriva S., Voges M.J.E.E.E., Sattely E.S., Garrido-Oter R., Schulze-Lefert P. |
| Rok vydání: | 2020 |
| Předmět: |
plant growth promotion
Iron Arabidopsis Secondary Metabolism Biology coumarin Microbiology Plant Roots Article iron nutrition Transcriptome 03 medical and health sciences chemistry.chemical_compound Soil 0302 clinical medicine Mediator Virology Arabidopsis thaliana Secretion heterocyclic compounds Symbiosis Phylogeny Soil Microbiology 030304 developmental biology root microbiota 0303 health sciences coumarins Arabidopsis Proteins secondary metabolites Gene Expression Profiling Microbiota fungi immune regulation food and beverages edaphic adaptation biology.organism_classification Commensalism Cell biology chemistry Rhizosphere Parasitology Fraxetin Adaptation 030217 neurology & neurosurgery |
| Zdroj: | Cell Host & Microbe |
| ISSN: | 1934-6069 |
| Popis: | Summary Plants benefit from associations with a diverse community of root-colonizing microbes. Deciphering the mechanisms underpinning these beneficial services are of interest for improving plant productivity. We report a plant-beneficial interaction between Arabidopsis thaliana and the root microbiota under iron deprivation that is dependent on the secretion of plant-derived coumarins. Disrupting this pathway alters the microbiota and impairs plant growth in iron-limiting soil. Furthermore, the microbiota improves iron-limiting plant performance via a mechanism dependent on plant iron import and secretion of the coumarin fraxetin. This beneficial trait is strain specific yet functionally redundant across phylogenetic lineages of the microbiota. Transcriptomic and elemental analyses revealed that this interaction between commensals and coumarins promotes growth by relieving iron starvation. These results show that coumarins improve plant performance by eliciting microbe-assisted iron nutrition. We propose that the bacterial root microbiota, stimulated by secreted coumarins, is an integral mediator of plant adaptation to iron-limiting soils. Graphical Abstract Highlights • Coumarins alter the root microbiota and improve plant growth in iron-limiting soil • The microbiota improves plant iron nutrition via a coumarin-dependent mechanism • The iron-beneficial commensal trait is taxonomically widespread but strain specific • Coumarin-microbiota interaction resolves iron starvation and regulates immune response Iron-limiting soils are widespread, causing significant losses in plant growth and productivity. Harbort et al. show that under iron limitation, plant-secreted coumarin compounds are mediators of a beneficial plant-microbiota interaction. These specialized metabolites alter root microbiota composition and are required for microbiota-mediated plant iron uptake and immune regulation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|