Additional file 5 of Integrated multiomic approach for identification of novel immunotherapeutic targets in AML

Autor: Köhnke, Thomas, Liu, Xilong, Haubner, Sascha, Bücklein, Veit, Hänel, Gerulf, Krupka, Christina, Solis-Mezarino, Victor, Herzog, Franz, Subklewe, Marion
Rok vydání: 2022
DOI: 10.6084/m9.figshare.20047209.v1
Popis: Additional file 5: Figure S1. Expression patterns and cut-off determination for AML Surfaceome. A: Expression of Surfaceome genes in hematopoietic stem cells in the bone marrow (HSCs – top panel), early hematopoietic progenitors in the bone marrow (HPC, middle panel) and CD14+ monocytes (bottom panel). Data derived from BloodSpot database (HemaExplorer). Cut-off used for filtering of Surfaceome candidates shown (calculated as the mean + SD). B: Expression of Surfaceome genes in non-hematopoietic tissue, displaying average non-heme tissue expression (top panel) or maximal non-heme tissue expression (from Genotype-Tissue Expression Project - GTEx). Cut-off used for filtering of Surfaceome candidates shown (calculated as the mean + SD).
Databáze: OpenAIRE