Preoperative Hypoalbuminemia Predicts Early Mortality Following Open Abdominal Surgery in Patients Above 60 Years of Age
| Autor: | L T Sørensen, D Hannani, Lars N. Jorgensen, Pia Bükmann Larsen, Henrik L. Jørgensen, S Liest |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Denmark Frail Elderly frailty 03 medical and health sciences 0302 clinical medicine Postoperative Complications Predictive Value of Tests Abdomen medicine gastrointestinal surgery Humans In patient 030212 general & internal medicine Hypoalbuminemia Registries Aged Retrospective Studies algorithm business.industry Albumin hypoalbuminemia Middle Aged medicine.disease abdominal surgery mortality Surgery 030220 oncology & carcinogenesis Female Plasma Albumin business Biomarkers Abdominal surgery |
| Zdroj: | Larsen, P B, Liest, S, Hannani, D, Jørgensen, H L, Sørensen, L T & Jørgensen, L N 2021, ' Preoperative Hypoalbuminemia Predicts Early Mortality Following Open Abdominal Surgery in Patients Above 60 Years of Age ', Scandinavian Journal of Surgery, vol. 110, no. 1, pp. 29-36 . https://doi.org/10.1177/1457496919888598 |
| ISSN: | 1799-7267 |
| DOI: | 10.1177/1457496919888598 |
| Popis: | Background: Major abdominal surgery in older and frail patients is associated with considerable morbidity and mortality. Plasma albumin is routinely measured in the clinic and has been proposed as an indicator of frailty. This study aimed to investigate if plasma albumin is a predictor of mortality in older patients undergoing open abdominal surgery. Materials and methods: We conducted a single-center, register-based retrospective study of patients, aged ⩾60 years who underwent one of 81 open abdominal surgical procedures. Patients operated on during the period from January 1st, 2000 to May 31st, 2013 were consecutively identified in the Danish National Patient Registry. Plasma albumin was measured within 30 days prior to surgery and the primary endpoint was 30-day postoperative mortality. Results: 3,639 patients were included of whom 68.2% underwent emergency surgery. The rate of severe hypoalbuminemia (plasma albumin Conclusion: Preoperative plasma albumin is a predictor of 30-day mortality in patients above 60 years of age following open abdominal surgery. Assessment of plasma albumin in conjunction with other risk factors such as age, sex, and surgical priority may improve preoperative decision-making. |
| Databáze: | OpenAIRE |
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