Age-related increase in xanthine oxidase activity in human plasma and rat tissues
Autor: | Rafael Aranda, Elena Domenech, Ariana Diana Rus, Juan Sastre, Jose Viña, José T. Real, Federico V. Pallardó |
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Rok vydání: | 2007 |
Předmět: |
Adult
Male medicine.medical_specialty Aging Xanthine Oxidase medicine.disease_cause Biochemistry chemistry.chemical_compound Superoxides Internal medicine medicine Animals Humans Prospective Studies Rats Wistar Xanthine oxidase Muscle Skeletal Aorta Aged Superoxide Skeletal muscle General Medicine Glutathione Middle Aged medicine.disease Rats Endocrinology medicine.anatomical_structure chemistry Ageing Heart failure Uric acid Female Oxidative stress |
Zdroj: | Free radical research. 41(11) |
ISSN: | 1071-5762 |
Popis: | This study assessed the role of xanthine oxidase in vascular ageing. A positive correlation between xanthine oxidase activity and age was found in human plasma. Similar results were found in rat plasma. Xanthine oxidase expression and activity in homogenates from the aortic wall were significantly higher in samples from old rats than in their young counterparts (p |
Databáze: | OpenAIRE |
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