Malaria at Parturition in Nigeria: Current Status and Delivery Outcome
| Autor: | O. A. Oguntayo, SK Ernest, T Oguonu, Michael V. Callahan, Olanrewaju T. Adedoyin, Davidson H. Hamer, H O Dada-Adegbola, Adeola A Orogade, Catherine O. Falade, Henrietta U. Okafor, Olugbenga A. Mokuolu |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Adolescent Article Subject Anemia Placenta Birth weight Nigeria Dermatology Parasitemia Hematocrit lcsh:Gynecology and obstetrics lcsh:Infectious and parasitic diseases Young Adult Pregnancy parasitic diseases Prevalence medicine Humans lcsh:RC109-216 Young adult Letter to the Editor lcsh:RG1-991 medicine.diagnostic_test business.industry Obstetrics Infant Newborn Parturition Pregnancy Outcome Obstetrics and Gynecology Infant Low Birth Weight medicine.disease Malaria Low birth weight Infectious Diseases Pregnancy Complications Parasitic Female medicine.symptom business Infant Premature Maternal Age Research Article |
| Zdroj: | Infectious Diseases in Obstetrics and Gynecology, Vol 2009 (2009) Infectious Diseases in Obstetrics and Gynecology |
| ISSN: | 1098-0997 1064-7449 |
| Popis: | Background. To evaluate the current status of malaria at parturition and its impact on delivery outcome in Nigeria.Methods. A total of 2500 mother-neonate pairs were enrolled at 4 sites over a 12-month period. Maternal and placental blood smears for malaria parasitaemia and haematocrit were determined.Results. Of the 2500 subjects enrolled, 625 were excluded from analysis because of breach in study protocol. The mean age of the remaining 1875 mothers was 29.0±5.1 years. The prevalence of parasitaemia was 17% and 14% in the peripheral blood and placenta of the parturient women, respectively. Peripheral blood parasitaemia was negatively associated with increasing parity (P<.0001). Maternal age<20 years was significantly associated with both peripheral blood and placental parasitaemia. After adjusting for covariates only age<20 years was associated with placental parasitaemia. Peripheral blood parasitaemia in the women was associated with anaemia (PCV≤30%) lower mean hematocrit (P<.0001). lower mean birth weight (P<.001) and a higher proportion of low birth weight babies (LBW), (P=.025).Conclusion. In Nigeria, maternal age<20 years was the most important predisposing factor to malaria at parturition. The main impacts on pregnancy outcome were a twofold increase in rate of maternal anaemia and higher prevalence of LBW. |
| Databáze: | OpenAIRE |
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