Biocidal action of chlorhexidine is annulled by nicotinic acid
| Autor: | Herman Baker, Elliott R. Baker, B DeAngelis, Oscar Frank |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Pharmacology
Niacinamide Nicotinamide Chlorhexidine Eukaryota Biological activity Metabolism Biology Niacin chemistry.chemical_compound Infectious Diseases Nicotinic agonist Biochemistry Mechanism of action chemistry medicine Escherichia coli Animals Pharmacology (medical) Drug Interactions medicine.symptom Growth inhibition Research Article |
| Zdroj: | Antimicrobial agents and chemotherapy. 38(10) |
| ISSN: | 0066-4804 |
| Popis: | An analytical system comprising a bacterium and a protozoan was used to pinpoint the metabolic lesion whereby chlorhexidine (CLX) produced cell death. Nicotinic acid but not nicotinamide annulled the biocidal action of CLX. The results suggest that CLX may not permit bioconversion of nicotinamide to nicotinic acid to annul the growth inhibition induced by CLX. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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