Cardiovascular remodeling is greater in isolated systolic hypertension than in diastolic hypertension in older adults: the Insufficienza Cardiaca negli Anziani Residenti (ICARE) a Dicomano Study

Autor: Gabriella Silvestrini, Francesca Bencini, Mary J. Roman, Walter De Alfieri, Niccolò Marchionni, Richard B. Devereux, Mauro Di Bari, Riccardo Pini, M. Chiara Cavallini, Giulio Masotti, Elisabetta Tonon
Rok vydání: 2002
Předmět:
Zdroj: Journal of the American College of Cardiology. 40:1283-1289
ISSN: 0735-1097
Popis: ObjectivesWe investigated cardiac and vascular remodeling in an unselected older population with either diastolic hypertension (HTN) or isolated systolic hypertension (ISH).BackgroundIsolated systolic hypertension accounts for a substantial proportion of hypertension in individuals older than 65 years and is strongly associated with an increased risk of cardiac and cerebrovascular events. The exact mechanisms underlying the increased risk associated with ISH and elevated pulse pressure (PP), in comparison with HTN, have not been extensively investigated.MethodsCommunity-dwelling residents age ≥65 years in a small town in Italy (Dicomano) were enrolled. Untreated subjects considered in this study included 173 normotensive subjects (blood pressure [BP]
Databáze: OpenAIRE