Interferometric technique to measure biomechanical changes in the cornea induced by refractive surgery
Autor: | Leon Lobo, John R. Tyrer, John C. Marshall, J. Ibrahim, Philip D. Jaycock |
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Rok vydání: | 2004 |
Předmět: |
medicine.medical_specialty
Intraocular pressure Light medicine.medical_treatment Hydrostatic pressure Keratomileusis Diagnostic Techniques Ophthalmological Surgical Flaps Cornea Microkeratome Ophthalmology Refractive surgery medicine Hydrostatic Pressure Animals Intraocular Pressure Sheep medicine.diagnostic_test business.industry Corneal Topography Corneal topography Elastic Tissue Refractive Errors eye diseases Sensory Systems Photorefractive keratectomy Elasticity Biomechanical Phenomena Refractive Surgical Procedures medicine.anatomical_structure Interferometry Surgery sense organs Collagen business |
Zdroj: | Journal of cataract and refractive surgery. 31(1) |
ISSN: | 0886-3350 |
Popis: | Purpose To develop a technique to quantify biomechanical changes in the cornea after microkeratome incisions as would be performed in laser in situ keratomileusis. Setting St Thomas' Hospital, London, and the Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, Loughborough, United Kingdom. Methods Corneal displacements of whole sheep eyes were studied under hydrostatic loading using electronic speckle pattern interferometry before and after microkeratome incisions. Results After hydrostatic loading, there was a 20.7% increase in corneal displacement in corneas with microkeratome incisions compared to unoperated corneas; this was statistically significant ( P = .0068, unpaired t test). Conclusions Results show that in the formation of the microkeratome flap, collagen fibers are severed and minimal biomechanical loading is distributed through the flap. Corneal biomechanical integrity is compromised after microkeratome incisions. |
Databáze: | OpenAIRE |
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