Transcranial direct current stimulation improves the QT variability index and autonomic cardiac control in healthy subjects older than 60 years
| Autor: | Nicola Petrocchi, Claudia Di Iorio, Fabiola Mastropietri, Damiano Magrì, Ilaria Parrotta, Matteo Pascucci, Gianfranco Piccirillo, Cristina Ottaviani, Claudia Fiorucci, Federica Moscucci |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Aging medicine.medical_treatment Blood Pressure 030204 cardiovascular system & hematology Baroreflex Transcranial Direct Current Stimulation 03 medical and health sciences Young Adult 0302 clinical medicine Heart Rate Heart rate Medicine Heart rate variability Humans Aged Original Research Temporal cortex QT variability Transcranial direct-current stimulation business.industry autonomic nervous system heart rate variability General Medicine Middle Aged Healthy Volunteers transcranial direct current stimulation aging Autonomic nervous system Blood pressure Clinical Interventions in Aging Brain stimulation Anesthesia Regression Analysis Female Geriatrics and Gerontology business 030217 neurology & neurosurgery |
| Zdroj: | Clinical Interventions in Aging |
| Popis: | Gianfranco Piccirillo,1 Cristina Ottaviani,2 Claudia Fiorucci,1 Nicola Petrocchi,2 Federica Moscucci,1 Claudia Di Iorio,1 Fabiola Mastropietri,1 Ilaria Parrotta,1 Matteo Pascucci,1 Damiano Magrì3 1Department of Cardiovascular, Respiratory, Nephrological, Anestesiological and Geriatric Sciences, “Sapienza” University, 2Neuroimaging Laboratory, IRCCS Santa Lucia Foundation, 3Department of Clinical and Molecular Medicine, University of Rome “Sapienza”, Rome,Italy Background: Noninvasive brain stimulation technique is an interesting tool to investigate the causal relation between cortical functioning and autonomic nervous system (ANS) responses. Objective: The objective of this report is to evaluate whether anodal transcranial direct current stimulation (tDCS) over the temporal cortex influences short-period temporal ventricular repolarization dispersion and cardiovascular ANS control in elderly subjects. Subjects and methods: In 50 healthy subjects (29 subjects younger than 60years and 21subjects older than 60years) matched for gender, short-period RR and systolic blood pressure spectral variability, QT variability index (QTVI), and noninvasive hemodynamic data were obtained during anodal tDCS or sham stimulation. Results: In the older group, the QTVI, low-frequency (LF) power expressed in normalized units, the ratio between LF and high-frequency (HF) power, and systemic peripheral resistances decreased, whereas HF power expressed in normalized units and α HF power increased during the active compared to the sham condition (P |
| Databáze: | OpenAIRE |
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