Microscopic Study of Nervous System Plasticity: Interactions of Sympathetic Nerves with Neurons of Intraocular Hippocampal Transplants
| Autor: | E. A. Mugantseva, G. I. Zhuravlev, Z. N. Zhuravleva |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Nervous system Pathology medicine.medical_specialty Sympathetic Nervous System Confocal Hippocampus Hippocampal formation Autonomic Nervous System General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Adventitia Parenchyma medicine Neuropil Animals Rats Wistar Neurons Neuronal Plasticity Chemistry Brain General Medicine Nerve Regeneration Rats Microscopy Electron 030104 developmental biology medicine.anatomical_structure nervous system Cervical ganglia 030217 neurology & neurosurgery |
| Zdroj: | Bulletin of experimental biology and medicine. 164(5) |
| ISSN: | 1573-8221 |
| Popis: | Functional interactions of sympathetic fibers innervating the iris with the neurons of central origin in intraocular transplants of the rat hippocampus were studied by optic, confocal, and electron microscopy. After formaldehyde fixation, fluorescent dye Dil was applied to the upper cervical ganglion; the dye migrated to the transplant by lateral diffusion via axons. Sympathetic nerves labeled with fluorescent dye grew into the neurotransplants along perivascular membranes of blood vessels. In addition, some fluorescent axons were identified in the transplant parenchyma. Electron microscopy showed large bundles of the peripheral type axons in the vascular adventitia and Schwann-axonal complexes in the transplant neuropil. Autonomic axons formed synaptic contacts with transplanted neurons. |
| Databáze: | OpenAIRE |
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