Multicenter validation of the magnetic resonance T2* technique for quantification of pancreatic iron
| Autor: | Nicolò Schicchi, Giuseppe Peritore, Emanuele Grassedonio, Paolo Preziosi, Vincenzo Positano, Antonino Vallone, Calogera Gerardi, Alessia Pepe, Ada Riva, Stefania Renne, Laura Pistoia, Gennaro Restaino, Angelo Peluso, Daniele De Marchi, Riccardo Righi, Antonella Meloni |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Siderosis Correlation coefficient Intraclass correlation Iron 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Iron overload Magnetic resonance imaging Pancreas Female Humans Magnetic Resonance Imaging Reproducibility of Results medicine Radiology Nuclear Medicine and imaging Multislice Neuroradiology medicine.diagnostic_test business.industry Ultrasound General Medicine medicine.disease medicine.anatomical_structure 030220 oncology & carcinogenesis Radiology business |
| Zdroj: | European radiology. 29(5) |
| ISSN: | 1432-1084 |
| Popis: | To assess the transferability of the magnetic resonance imaging (MRI) multislice multiecho T2* technique for pancreatic iron overload assessment. Multiecho T2* sequences were installed on ten 1.5-T MRI scanners of the three main vendors. Five healthy subjects (n = 50) were scanned at each site. Five patients with thalassemia (n = 45) were scanned locally at each site and were rescanned at the reference site within 1 month. T2* images were analyzed using a previously validated software and the global pancreatic T2* value was calculated as the mean of T2* values over the head, body, and tail. T2* values of healthy subjects were above 26 ms and showed inter-site homogeneity. The T2* values measured in the MRI sites were comparable to the correspondent values observed in the reference site (12.02 ± 10.20 ms vs 11.98 ± 10.47 ms; p = 0.808), and the correlation coefficient was 0.978 (p |
| Databáze: | OpenAIRE |
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