Simultaneous couch and gantry dynamic arc rotation (CG-Darc) in the treatment of breast cancer with accelerated partial breast irradiation (APBI): a feasibility study
| Autor: | C. Popescu, Maria T. Vlachaki, V. Patenaude, Ivo A. Olivotto, Wayne Beckham |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
medicine.medical_treatment Breast Neoplasms Patient Positioning Arc (geometry) breast cancer Breast cancer medicine Radiation Oncology Physics Humans Dosimetry Radiology Nuclear Medicine and imaging In patient Radiometry Instrumentation Aged partial breast radiation Radiation business.industry Partial Breast Irradiation Radiotherapy Dosage Middle Aged medicine.disease Radiotherapy Computer-Assisted Radiation therapy 3D CRT Ipsilateral breast Feasibility Studies Female Radiotherapy Intensity-Modulated CG‐Darc business Dose rate Nuclear medicine RapidArc |
| Zdroj: | Journal of Applied Clinical Medical Physics |
| ISSN: | 1526-9914 |
| DOI: | 10.1120/jacmp.v14i1.4035 |
| Popis: | The purpose of this study was to compare the dosimetry of CG‐Darc with three‐dimensional conformal radiation therapy (3D CRT) and volumetric‐modulated arc therapy (RapidArc) in the treatment of breast cancer with APBI. CG‐Darc plans were generated using two tangential couch arcs combined with a simultaneous noncoplanar gantry arc. The dynamic couch arc was modeled by consecutive IMRT fields at 10° intervals. RapidArc plans used a single partial arc with an avoidance sector, preventing direct beam exit into the thorax. CG‐Darc and RapidArc plans were compared with 3D CRT in 20 patients previously treated with 3D CRT (group A), and in 15 additional patients who failed the dosimetric constraints of the Canadian trial and of NSABP B‐39/RTOG 0413 for APBI (group B). CG‐Darc resulted in superior target coverage compared to 3D CRT and RapidArc (V95%: 98.2% vs. 97.1% and 95.7%). For outer breast lesions, CG‐Darc and RapidArc significantly reduced the ipsilateral breast V50% by 8% in group A and 15% in group B (p |
| Databáze: | OpenAIRE |
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