DISTINGUISHING FEATURES OF MUSCULOSKELETAL SYSTEM EXTRAINTESTINAL MANIFESTATIONS IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE
| Autor: | V. M. Zhdan, O. A. Kyrian, M. Yu. Babanina M., L. M. Shilkina, O. I. Katerenchuk |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
business.industry lcsh:R dysbiosis lcsh:Medicine extraintestinal manifestations medicine.disease inflammatory bowel diseases spine Inflammatory bowel disease Gastroenterology inflammation activity lcsh:Biology (General) joints Internal medicine medicine In patient business lcsh:QH301-705.5 |
| Zdroj: | Вісник проблем біології і медицини, Vol 1, Iss 4, Pp 89--3 (2019) |
| ISSN: | 2523-4110 2077-4214 |
| DOI: | 10.29254/2077-4214-2019-4-1-153-89-93 |
| Popis: | Inflammatory bowel diseases (IBDs) that are accompanied by extraintestinal manifestations often lead to complications, contribute to deterioration of the quality of life and are difficult to diagnose. Therefore, the purpose of our research was to investigate the distinguishing features of the spine and joints lesions in patients with ulcerative colitis (UC) and Crohn’s disease (CD), which are the most frequent extraintestinal manifestations of the forenamed diseases, and to investigate the possible link between the gut microbiota dysbiosis and the disease activity. The data of 73 patients with IBDs, whose average age was 38,6±6,9, were analyzed in this research. Among the examined patients the first group consisted of 29 (39,7%) patients with IBDs and lesions of the spine and joints and the second group consisted of 44 patients without changes in the musculoskeletal system. UC was diagnosed more frequently – in 58 (79,5%) patients, – and CD was diagnosed in 15 (20,5%) patients; the large intestine lesions were detected significantly more often (р |
| Databáze: | OpenAIRE |
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