High-Dose-Rate Brachytherapy in the Treatment of Carcinoma of the Prostate
| Autor: | Sherief H. Gamie, Ajmel A. Puthawala, Joel M. Cherlow, Anil Sharma, Adina Londrc, Ko Sj, Nazmy N, A.M.N. Syed, Sheikh Km, Steven J Damore |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Male
Oncology medicine.medical_specialty Time Factors medicine.medical_treatment Brachytherapy Adenocarcinoma Disease-Free Survival 03 medical and health sciences 0302 clinical medicine Prostate Internal medicine Carcinoma Humans Medicine Aged Neoplasm Staging Aged 80 and over Tumor size business.industry Prostatectomy Prostatic Neoplasms Dose-Response Relationship Radiation Radiotherapy Dosage Hematology General Medicine Middle Aged Prostate-Specific Antigen Iridium Radioisotopes medicine.disease High-Dose Rate Brachytherapy Radiation therapy Treatment Outcome medicine.anatomical_structure 030220 oncology & carcinogenesis Localized disease 030211 gastroenterology & hepatology Radiology business |
| Zdroj: | Cancer Control. 8:511-521 |
| ISSN: | 1073-2748 |
| DOI: | 10.1177/107327480100800606 |
| Popis: | Background Although radical prostatectomy for localized disease is considered as a standard of care, external-beam radiotherapy and brachytherapy are equally effective. We report on the technique and preliminary results of high-dose-rate (HDR) brachytherapy using a temporary iridium-192 implant technique. Methods The authors reviewed the literature on the techniques, treatment protocols, and results of HDR brachytherapy in the treatment of carcinoma of the prostate, and they report their own protocols, technique, and results. Results The combination of HDR brachytherapy and external irradiation has been well tolerated by all 200 patients in our series, with less than 3% grade 3 late complications and with 95% PSA relapse-free survival with a median follow-up of 24 months. Conclusions HDR brachytherapy may be the most conformal type of irradiation in the treatment of carcinoma of the prostate regardless of tumor size, anatomical distortion, and organ mobility. |
| Databáze: | OpenAIRE |
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