Measurement of serum transferrin by the γ−γ perturbed angular correlation method
| Autor: | Duanzhi Yin, Jinlong Xu, Chongwen Sun, Wenbiao Chen, Xinbo Ni, Yongxian Wang, Sheng Ding |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
chemistry.chemical_classification
Endocrinology Diabetes and Metabolism Indium Radioisotopes Liver Neoplasms Biochemistry (medical) Clinical Biochemistry Transferrin Analytical chemistry General Medicine Normal serum Biochemistry Molecular conformation Inorganic Chemistry Nuclear magnetic resonance chemistry Gamma Rays Angular correlation Attenuation factor Humans Time integral Mathematics |
| Zdroj: | Biological Trace Element Research. 22:1-7 |
| ISSN: | 1559-0720 0163-4984 |
| DOI: | 10.1007/bf02917411 |
| Popis: | In this work, the average perturbed angular correlation integral attenuation factor G2 of the transferrin in the serums from the normals and the patients with liver cancer were determined using time integral perturbed angular correlation method (PAC). The average values of G2 were 0.1945 +/- 0.0155 for the cancer serum transferrin and 0.2865 +/- 0.0411 for the normal serum transferrin. The difference between these two groups is significant. Mathematical deduction and theoretical analysis suggested that the equivalent radius of the transferrin molecules in the serum of cancer patients becomes smaller than normal, because of a change in the molecular conformation. Similar results were also observed in experiments with rat serum transferrin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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