Extracorporeal irradiation of tumorous calvaria
| Autor: | Isaac L. Wornom, Matthew A. Manning, William C. Broaddus, Brian D. Kavanagh, Robert M. Cardinale, Rupert Schmidt-Ullrich |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Skull Neoplasms Calvaria Transplantation Autologous Surgical Flaps Extracorporeal Meningioma Meningeal Neoplasms medicine Humans Neoplasm Invasiveness Craniotomy business.industry Skull Middle Aged medicine.disease Surgery Radiation therapy Transplantation Frontal bone medicine.anatomical_structure Neoplasm Recurrence Local business Recurrent Meningioma |
| Zdroj: | Journal of Neurosurgery. 93:494-497 |
| ISSN: | 0022-3085 |
| DOI: | 10.3171/jns.2000.93.3.0494 |
| Popis: | ✓ This patient with recurrent meningioma grossly involving the frontal bone underwent craniotomy and tumor resection. During the procedure a bone flap was irradiated extracorporeally at a very high dose (120 Gy) sufficient to sterilize residual tumor cells, and the bone was then successfully replaced orthotopically for reconstruction. The use of autologous irradiated bone in this setting offers advantages over cadaveric transplantation and prosthetic implants. Radiation might cause less disruption of the bone's architecture than other techniques of tumor cell eradication. |
| Databáze: | OpenAIRE |
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