Chemical and pharmacological studies on Talauma ovata St. Hil. (Magnoliaceae)
| Autor: | Rosa Maria Ribeiro do Valle, Edelton Flávio Morato, Gina Struffaldi Morato, Reinaldo N. Takahashi, Thereza Christina Monteiro de Lima, Mauro Nicolau, Rosendo A. Yunes, Luiz Filipe Alves Cordeiro, João B. Calixto, Giles A. Rae |
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| Rok vydání: | 1989 |
| Předmět: |
Male
endocrine system Guinea Pigs Population In Vitro Techniques Biology Pharmacognosy complex mixtures Lethal Dose 50 Mice Drug Discovery Botany Animals Hypoglycemic Agents education Talauma ovata Pharmacology Folk medicine education.field_of_study Plants Medicinal Traditional medicine Plant Extracts Rats Inbred Strains Biological activity biology.organism_classification Rats Magnoliaceae Parasympathomimetics Female |
| Zdroj: | Journal of Ethnopharmacology. 26:277-286 |
| ISSN: | 0378-8741 |
| Popis: | Antidiabetic activity of crude extract of leaves of Talauma ovata St. Hil. (Magnoliaceae) was analysed as part of a general pharmacological screening of this plant. Chemical analysis demonstrated the presence of phytosteroids, saponins, alkaloids and tannins in the crude extract. Pharmacological studies failed to demonstrate hypoglycemic effect of this plant in normoglycemic, hyperglycemic or alloxan-diabetic rats. The low LD50 obtained for this plant strongly suggests that its consumption by the population may be hazardous. |
| Databáze: | OpenAIRE |
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