Stress Echocardiography and Strain in Aortic Regurgitation (SESAR protocol): Left ventricular contractile reserve and myocardial work in asymptomatic patients with severe aortic regurgitation
Autor: | Francesco Giallauria, Antonello D'Andrea, Tiziana Formisano, Giampaolo Tocci, Giuseppe Ambrosio, Maurizio Tusa, Maurizio Galderisi, Simona Sperlongano, Matteo Cameli, Eugenio Picano, Giovanni Corrado, Quirino Ciampi, Eduardo Bossone, Rodolfo Citro, Giuseppina Novo |
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Přispěvatelé: | D'Andrea, Antonello, Sperlongano, Simona, Formisano, Tiziana, Tocci, Giampaolo, Cameli, Matteo, Tusa, Maurizio, Novo, Giuseppina, Corrado, Giovanni, Ciampi, Quirino, Citro, Rodolfo, Bossone, Eduardo, Galderisi, Maurizio, Giallauria, Francesco, Ambrosio, Giuseppe, Picano, Eugenio, D'Andrea A., Sperlongano S., Formisano T., Tocci G., Cameli M., Tusa M., Novo G., Corrado G., Ciampi Q., Citro R., Bossone E., Galderisi M., Giallauria F., Ambrosio G., Picano E., D'Andrea, A, Sperlongano, S, Formisano, T, Tocci, G, Cameli, M, Tusa, M, Novo, G, Corrado, G, Ciampi, Q, Citro, R, Bossone, E, Galderisi, M, Giallauria, F, Ambrosio, G, Picano, E |
Rok vydání: | 2020 |
Předmět: |
aortic regurgitation
contractile reserve myocardial work stress echocardiography two-dimensional strain Male medicine.medical_specialty Longitudinal strain stress echocardiography Heart Ventricles Aortic Valve Insufficiency Strain (injury) Regurgitation (circulation) 030204 cardiovascular system & hematology Asymptomatic two-dimensional strain Ventricular Function Left Heart Ventricle 03 medical and health sciences Ventricular Dysfunction Left 0302 clinical medicine Internal medicine contractile reserve Echocardiography Stre medicine Stress Echocardiography Humans Radiology Nuclear Medicine and imaging 030212 general & internal medicine Subclinical infection Ejection fraction business.industry Stroke Volume aortic regurgitation myocardial work medicine.disease Lung ultrasound Cardiology medicine.symptom Cardiology and Cardiovascular Medicine business Human Echocardiography Stress |
Zdroj: | Echocardiography (Mount Kisco, N.Y.)REFERENCES. 37(8) |
ISSN: | 1540-8175 |
Popis: | Objectives: To analyze left ventricular (LV) myocardial deformation and contractile reserve (CR) in asymptomatic patients with severe aortic regurgitation (AR) at rest and during exercise, and their correlation with functional capacity. Background: The natural history of chronic AR is characterized by a prolonged silent phase before onset of symptoms and overt LV dysfunction. Assessment of LV systolic function and contractile reserve has an important role in the decision-making of AR asymptomatic patients. Methods: Standard echo, lung ultrasound, and LV 2D speckle tracking strain were performed at rest and during exercise in asymptomatic patients with severe AR and in age- and sex-comparable healthy controls. Results: 115 AR patients (male sex 58.2%; 52.3±18.3years) and 55 controls were enrolled. Baseline LV ejection fraction was comparable between the groups. Resting LV global longitudinal strain (GLS) and myocardial work efficiency (MWE) were significantly reduced in AR (GLS-15.8±2.8 vs −21.4±4.4; P  |
Databáze: | OpenAIRE |
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