Post-chemotherapy neuropathy
| Autor: | Ricardo Caponero, Silvia Maria Machado Tahamtani, Emily Santos Montarroyos |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment lcsh:Medicine Neuropathic pain law.invention Randomized controlled trial law Chemotherapy Medicine Adverse effect Intensive care medicine lcsh:R5-920 Modalities Adverse effects business.industry lcsh:R dor neuropática medicine.disease efeitos adversos Pathophysiology Neuropathy neuropatia Peripheral neuropathy Systematic review Physical therapy lcsh:Medicine (General) business quimioterapia |
| Zdroj: | Revista Dor, Vol 17, Iss suppl 1, Pp 56-58 Revista Dor v.17 suppl.1 2016 Revista Dor Sociedade Brasileira para o Estudo da Dor (SBED) instacron:SBED |
| ISSN: | 1806-0013 |
| DOI: | 10.5935/1806-0013.20160049 |
| Popis: | BACKGROUND AND OBJECTIVES: Anticancer chemotherapeutics can induce painful peripheral neuropathy. Symptoms range widely and can involve sensory, motor, and autonomic systems. However, chemotherapy-induced peripheral neuropathy is under-assessed and undertreated and its diagnosis is somewhat complicated by the lack of consensus on its pathophysiology and presentation. The objective of this study was to review medical publications in English, Spanish and Portuguese, in the last ten years, about painful peripheral neuropathy. CONTENTS: Systematic literature review on painful peripheral neuropathy associated with systemic anticancer chemotherapy. CONCLUSION: Although limited reliable evidence regarding the appropriate treatment for this condition exists, it is based on current neuropathic pain guidelines. Further studies on differences between the pathophysiology of chemotherapy-induced peripheral neuropathy and those of other neuropathic pain conditions may lead to the development of more effective treatment modalities. Additionally, therapeutic strategies for the management of chemotherapy-induced peripheral neuropathy must be validated by large-scale randomized clinical trials to meet the demands of evidenced-based medicine. |
| Databáze: | OpenAIRE |
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