Aborted myocardial infarction in patients with ST-segment elevation
| Autor: | Taha Taher, Frans Van de Werf, Christopher B. Granger, Shaun G. Goodman, Claudio Fresco, Galen S. Wagner, F.W. Verheugt, Yuling Fu, Lars Wallentin, Paul W. Armstrong |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test Heart disease business.industry ST elevation medicine.disease Regimen Reperfusion therapy Internal medicine Cardiology Medicine ST segment cardiovascular diseases Myocardial infarction Cardiology and Cardiovascular Medicine business Electrocardiography Fibrinolytic agent |
| Zdroj: | Journal of the American College of Cardiology. 44:38-43 |
| ISSN: | 0735-1097 |
| DOI: | 10.1016/j.jacc.2004.03.041 |
| Popis: | Objectives The investigators undertook a systematic, comprehensive analysis of the therapeutic response and clinical outcomes of reperfusion therapy for acute ST-segment elevation myocardial infarction (STEMI) in 5,470 patients from the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen (ASSENT)-3 trial. Background Prompt effective reperfusion therapy for acute STEMI may attenuate major myocardial necrosis. Methods We prospectively collected sequential electrocardiographs and clinical data. Aborted myocardial infarction (MI) was defined as maximal creatine kinase ≤2× upper limit of normal coupled with typical evolutionary electrocardiographic changes. Results Of the patients, 727 (13.3%) had an aborted MI, with the highest frequency (25%) occurring in patients treated Conclusions Prompt fibrinolytic treatment improved the likelihood of aborted MI. The subgroup with complete 60-min ST-segment resolution had the best clinical outcomes. |
| Databáze: | OpenAIRE |
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