Glycoprotein synthesis in developing sea urchin embryos

Autor: Alfred E. Brown, H.Bruce Bosmann
Rok vydání: 1978
Předmět:
Zdroj: Biochemical and Biophysical Research Communications. 80:833-840
ISSN: 0006-291X
DOI: 10.1016/0006-291x(78)91320-7
Popis: Surface membrane glycoproteins have been postulated in many mammalian cells to be involved in external surface membrane functions such as cell adhesion, cell-cell recognition, and cell movement. In developing echinoderm embryos, cell adhesion, recognition, and movement of individual cell types have been attributed to differences in the external surface membranes of these cells. Results reported here suggest that the three cell types of 16-cell sea urchin embryos have a mechanism that could establish differences in the carbohydrate portion of glycoproteins located in the external surface membrane. The results demonstrate 1) that glycoproteins are synthesized during early sea urchin development and 2) that slightly different rates of glycoprotein synthesis exist for the three types of blastomeres from 16-cell sea urchin embryos.
Databáze: OpenAIRE