Complete genome sequence of an extensively drug resistant (XDR) M. morganii SMM01 isolated from a patient with urinary and fecal incontinence
Autor: | Arun Sai Kumar Peketi, Eswarappa Pradeep Bulagonda, Valakunja Nagaraja, Prakash Kumar, Manmath Lama, Balaram Khamari, Pachi Pulusu Chanakya |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Pseudogene
Health Informatics Drug resistance Biology Data Note Genome Hybrid sequencing Antibiotic resistance Extensively drug resistant (XDR) Drug Resistance Bacterial Genetics Humans Complete genome and antimicrobial resistance (AMR) Child Genome size Gene Whole genome sequencing Morganella morganii Genomics M. morganii Anti-Bacterial Agents Pharmaceutical Preparations GC-content Fecal Incontinence Genome Bacterial |
Zdroj: | BMC Genomic Data |
ISSN: | 2730-6844 |
Popis: | Objective M. morganii is a gram-negative, non-lactose fermenting and an opportunistic pathogen frequently associated with nosocomial infections. Although first isolated in 1906 from a pediatric fecal sample, not many M. morganii isolates have been sequenced. The objective of this work is to determine the complete genome sequence of an XDR M. morganii strain (SMM01) isolated from the urine of a patient with urinary and fecal incontinence and to characterize its antimicrobial resistance profile. Data description Here, we report the complete genome sequence of M. morganii SMM01 generated from the hybrid assembly of Illumina HiSeq X and Nanopore MinION reads. The assembly is 100% complete with genome size of 39,30,130 bp and GC content of 51%. Genomic features include 3617 CDS, 18 rRNAs, 78 tRNAs, 4 ncRNAs and 60 pseudogenes. Antimicrobial resistance profile was characterized by the presence of genes conferring resistance to aminoglycosides, β-lactams, fluoroquinolones, chloramphenicol, and tetracyclines. Secondary metabolite biosynthetic gene clusters like NRPS, T1PKS, thiopeptide, beta-lactone, and bacteriocin were identified. The genome data described here would be the first complete genome of an Indian M. morganii isolate providing crucial information on antimicrobial resistance patterns, paving the way for further comparative genome analyses. |
Databáze: | OpenAIRE |
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