Heavy-density Particles of Australia Antigen Detected in a Human Plasma Pool
| Autor: | Ryoichi Shirachi, Noriyoshi Sukeno, Nakao Ishida, Takusei Umenai |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Immunodiffusion
viruses Complement Fixation Tests Cesium Fraction (chemistry) General Medicine Plasma Hepatitis A Biology Ouchterlony double immunodiffusion Complement fixation test Virology General Biochemistry Genetics and Molecular Biology Staining Hepatitis B Antigens Microscopy Electron Chlorides Antigen Carrier State Blood plasma Centrifugation Density Gradient Biophysics Humans Au antigen Immunoelectrophoresis |
| Zdroj: | The Tohoku Journal of Experimental Medicine. 107:359-365 |
| ISSN: | 1349-3329 0040-8727 |
| Popis: | Biophysical study of Australia antigen (Au) was made with 5 specimens including 3 plasmas and 2 plasma pools which had been known to be Au carriers. A fraction which could be detected both by complement fixation test and by Ouchterlony double diffusion test was obtained with all of the specimens and this could be banded at a buoyant density of 1.21-1.23g/cm3 in CsCl. In addition, another fraction with a buoyant density of 1.28g/cm3 was recovered from one of the plasma pools. This fraction was detected, however, only by complement fixation test. Electron microscopic study of the latter fraction revealed small particles about 3-4 mμ in diameter, suggesting subunits of known Au antigen particles. |
| Databáze: | OpenAIRE |
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