Is CEA analysis of value in screening for recurrences after surgery for colorectal carcinoma?
| Autor: | Göran Ekelund, Ulf Carlsson, Bertil Nosslin, L Leandoer, Jan Stewénius |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Male
Reoperation medicine.medical_specialty Blood Chemistry Test Colorectal cancer Blood Sedimentation Hemoglobins Carcinoembryonic antigen Surgical oncology medicine Humans Aspartate Aminotransferases biology Rectal Neoplasms business.industry Gastroenterology Alanine Transaminase gamma-Glutamyltransferase General Medicine Alkaline Phosphatase medicine.disease Predictive value digestive system diseases Colorectal surgery Carcinoembryonic Antigen Surgery Clinical diagnosis Colonic Neoplasms biology.protein Female Neoplasm Recurrence Local business CEA measurement |
| Zdroj: | Diseases of the Colon & Rectum. 26:369-373 |
| ISSN: | 0012-3706 |
| DOI: | 10.1007/bf02553376 |
| Popis: | The progress of 139 patients operated upon for cure of colorectal carcinoma, was followed postoperatively with a standardized protocol. A CEA test was performed for comparison with other parameters. Median observation time was four years. When an upper limit for CEA of 7.5 micrograms/1 was allowed, sensitivity was found to be 78 per cent, specificity 91 per cent, and predictive value of an elevated CEA concentration, 83 per cent. In general, CEA measurement traced recurrence six months before clinical diagnosis. In only a few cases was recurrence first heralded by an abnormality in other blood chemistry test results. CEA may thus be used in postoperative screening for recurrence even though most recurrences, when detected, are not curable. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink