Detection of leucochimaerism in bovine twins by DNA fingerprinting

Autor:	Sheila M. Schmutz, K. D. M. Lang, Y. Plante, J. S. Moker
Rok vydání:	2009
Předmět:	Male medicine.medical_specialty X Chromosome Genotype Dizygotic twin Biology Y chromosome Chimera (genetics) Y Chromosome Leukocytes Twins Dizygotic Genetics medicine Animals X chromosome Chimera Cytogenetics Karyotype General Medicine DNA Fingerprinting Pedigree DNA profiling Genetic marker Karyotyping Cattle Female Animal Science and Zoology
Zdroj:	Animal Genetics. 23:295-302
ISSN:	1365-2052 0268-9146
DOI:	10.1111/j.1365-2052.1992.tb00151.x
Popis:	Karyotyping and hypervariable genetic markers indicate extensive leucochimaerism between pairs of dizygotic twins in cattle, a result of placental vascular anastomosis. The extent of this chimaerism includes both kind and number of cells exchanged. All heterosexual twin pairs harboured two types of leucocytes, having either XX or XY chromosome pairs, and 30 of 31 pairs of twins shared identical DNA fingerprints. Although chromosome results from skin fibroblasts indicate that some chimaerism occurs in the skin, the low level allows for differentiation of genotypes between twins. The results warrant against the common practice of using blood samples for DNA typing if twinning is not properly documented.
Databáze:	OpenAIRE
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