Adolescence transitional care in neurogenic detrusor overactivity and the use of OnabotulinumtoxinA: A clinical algorithm from an Italian consensus statement
| Autor: | Valerio Iacovelli, Andrea Tubaro, Antonio Marte, Giovanni Mosiello, Antonella Giannantoni, Enrico Finazzi Agrò, Antonio Carbone, Stefania Musco, Mario De Gennaro, Roberto Carone, Giulio Del Popolo, Giovanni Palleschi |
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| Přispěvatelé: | Giovanni, Palleschi, Giovanni, Mosiello, Valerio, Iacovelli, Stefania, Musco, Giulio Del, Popolo, Antonella, Giannantoni, Antonio, Carbone, Roberto, Carone, Andrea, Tubaro, Mario De, Gennaro, Marte, Antonio, Enrico Finazzi, Agrò |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty Transition to Adult Care Consensus Adolescent Urology 030232 urology & nephrology Delphi method Alternative medicine adolescence neurogenic detrusor overactivity onabotulinumtoxinA transitional care Settore MED/24 - Urologia 03 medical and health sciences Young Adult 0302 clinical medicine Multidisciplinary approach adolescence neurogenic detrusor overactivity onabotulinumtoxinA transitional care medicine Humans Transitional care Young adult Botulinum Toxins Type A Urinary Bladder Neurogenic Statement (computer science) 030219 obstetrics & reproductive medicine business.industry Urinary Bladder Overactive Adolescence Neurogenic detrusor overactivity OnabotulinumtoxinA Neurology (clinical) Pediatric urology Clinical algorithm Neuromuscular Agents Family medicine Physical therapy Female business Algorithms |
| Popis: | Aims OnabotulinumtoxinA (onaBNTa) for treating neurogenic detrusor overactivity (NDO) is widely used after its regulatory approval in adults. Although the administration of onaBNTa is still considered off-label in children, data have already been reported on its efficacy and safety. Nowadays, there is a lack of standardized protocols for treatment of NDO with onaBNTa in adolescent patients in their transition from the childhood to the adult age. With the aim to address this issue a consensus panel was obtained. Methods A panel of leading urologists and urogynaecologists skilled in functional urology, neuro-urology, urogynaecology, and pediatric urology participated in a consensus-forming project using a Delphi method to reach national consensus on NDO—onaBNTa treatment in adolescence transitional care. Results In total, 11 experts participated. All panelists participated in the four phases of the consensus process. Consensus was reached if ≥70% of the experts agreed on recommendations. To facilitate a common understanding among all experts, a face-to-face consensus meeting was held in Rome in march 2015 and then with a follow-up teleconference in march 2017. By the end of the Delphi process, formal consensus was achieved for 100% of the items and an algorithm was then developed. Conclusions This manuscript represents the first report on the onaBNTa in adolescents. Young adults should be treated as a distinct sub-population in policy, planning, programming, and research, as strongly sustained by national public health care. This consensus and the algorithm could support multidisciplinary communication, reduce the extent of variations in clinical practice and optimize clinical decision making. |
| Databáze: | OpenAIRE |
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