Alkaline phosphatase isoenzyme in intestinal metaplasia of the stomach
| Autor: | Miki Kazumasa, Oda Toshitsugu, Suzuki Hiroshi, Uno Shiro, Niwa Hirohumi |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
musculoskeletal diseases
Peptic Ulcer medicine.medical_specialty Pathology Clinical Biochemistry Radioimmunoassay Gastric carcinoma digestive system Biochemistry Gastroenterology stomatognathic system Stomach Neoplasms Internal medicine medicine Humans Metaplasia biology Chemistry musculoskeletal neural and ocular physiology Stomach Biochemistry (medical) Intestinal metaplasia General Medicine Alkaline Phosphatase medicine.disease Radioimmunoassay technique Alkaline phosphatase isoenzymes digestive system diseases Staining Intestines Isoenzymes medicine.anatomical_structure Gastric Mucosa biology.protein Alkaline phosphatase Antibody |
| Zdroj: | Clinica Chimica Acta. 76:79-88 |
| ISSN: | 0009-8981 |
| Popis: | To investigate the relationship of intestinal metaplasia of the stomach and gastric carcinoma, isoenzymatic analysis of alkaline phosphatase (ALP) of the intestinal metaplasia was studied. Purified human intestinal ALP, and anti-human intestinal ALP antibody were used, and mucosa ALP of the other segments of human gastro-intestinal tract was studied simultaneously. Radioimmunoassay technique, and immunofluorescent staining using anti-human intestinal ALP antibody, were applied to the stomachs resected for gastric carcinoma or peptic ulcer. ALP extracted from the mucosa of intestinal metaplasia, and from the mucosa of the other segments of human gastro-intestinal tract, was identical with intestinal ALP in its enzymological and immunological properties. |
| Databáze: | OpenAIRE |
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