Rh antibody stimulation with an Rh-negative fetus (Rh anamnestic reaction) and its significance to the newborn

Autor: L. Ange Kozlow, Donald C. Beaver, Wolf W. Zuelzer, Charles L. Schneider
Rok vydání: 1950
Předmět:
Zdroj: American journal of obstetrics and gynecology. 59(3)
ISSN: 0002-9378
Popis: 1. The Rh anamnestic reaction was studied in three rh-negative mothers. Each had become previously sensitized to the D factor. High anti-D titers developed in dd mothers although this time carrying dd fetuses. 2. Because the course of antibody levels resembles that of incompatible pregnancies, it is concluded that it is not possible to distinguish, by means of the antibody behavior alone, between a benign anamnestic reaction and one which may lead to erythroblastosis. 3. In each of the three cases studied, pregnancy had been electively terminated because of concern for the fetus. The three babies were without signs of erythroblastosis fetalis, although one infant died from respiratory complications incidental to the intervention. 4. It is concluded that obstetric or pediatric intervention based on maternal Rh antibody production alone is not well advised. Intervention may serve only to expose mother or child or both to such risks as are inherent in the interventions themselves.
Databáze: OpenAIRE