Prevalence of rhinoviruses in young children of an unselected birth cohort from the Netherlands
| Autor: | W.M.C. van Aalderen, P. J. Sterk, Aline B. Sprikkelman, Dasja Pajkrt, René Minnaar, Simone Hashimoto, Katja C. Wolthers, Kimberley S. M. Benschop, Joanne G. Wildenbeest, Eric G. Haarman, M.P. van der Schee |
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| Přispěvatelé: | Pediatric surgery, AII - Infectious diseases, Paediatric Infectious Diseases / Rheumatology / Immunology, Medical Microbiology and Infection Prevention, Pulmonology, Paediatric Pulmonology |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Male Pediatrics medicine.medical_specialty Rhinovirus 030106 microbiology RV type C medicine.disease_cause Asymptomatic Severity of Illness Index Article Cohort Studies 03 medical and health sciences 0302 clinical medicine medicine Prevalence Journal Article Humans 030212 general & internal medicine Children Asthma Netherlands Picornaviridae Infections Respiratory tract infections Wheezing business.industry Coinfection Respiratory disease Infant General Medicine Bacterial Infections medicine.disease Unselected birth cohort Infectious Diseases Bronchiolitis Case-Control Studies Child Preschool Cohort Respiratory virus Female Seasons medicine.symptom business Follow-Up Studies |
| Zdroj: | Clinical Microbiology and Infection, 22(8), 736.e9. Elsevier Limited Clinical Microbiology and Infection Clinical Microbiology and Infection, 22(8) Clinical microbiology and infection, 22(8), 736.e9-736.e15. Elsevier Limited Wildenbeest, J G, van der Schee, M P C, Hashimoto, S, Benschop, K S M, Minnaar, R P, Sprikkelman, A B, Haarman, E G, van Aalderen, W M C, Sterk, P J, Pajkrt, D & Wolthers, K C 2016, ' Prevalence of rhinoviruses in young children of an unselected birth cohort from the Netherlands ', Clinical Microbiology and Infection, vol. 22, no. 8 . https://doi.org/10.1016/j.cmi.2016.05.022 |
| ISSN: | 1198-743X |
| Popis: | Rhinovirus (RV) is a frequent pathogen in young children, eliciting symptoms ranging from common colds to wheezing illnesses and lower respiratory tract infections. The recently identified RV-C seems to be associated with asthma exacerbations and more severe disease, but results vary. We studied the prevalence and severity of infection with RV in an unselected birth cohort. Children with respiratory symptoms entered the symptomatic arm of the cohort and were compared with asymptomatic children. Severity of wheezing and other respiratory symptoms was registered. Respiratory viruses were evaluated using throat and nasopharyngeal swabs on first presentation and after recovery (wheezing children). RV genotyping was performed on RV-PCR positive samples. RV was the most prevalent respiratory virus and was found in 58/140 symptomatic children (41%), 24/96 (25%) control children and 19/74 (26%) wheezing symptomatic children after recovery (p |
| Databáze: | OpenAIRE |
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