Elicitation of transient lower oesophageal sphincter relaxations in response to gastric distension and meal ingestion
| Autor: | Robert C.H. Scheffer, Hein G. Gooszen, A. J. P. M. Smout, J. M. M. Roelofs, Louis M. A. Akkermans, J. E. Bais |
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| Přispěvatelé: | Other departments |
| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Oesophageal manometry Physiology Manometry Muscle Relaxation Distension Gastroenterology Gastric barostat Internal medicine medicine Pressure Lower oesophageal sphincter Humans Meal Endocrine and Autonomic Systems business.industry Gastric distension digestive oral and skin physiology Stomach Postprandial Period Barostat Meal ingestion Gastroesophageal Reflux Female Esophagogastric Junction medicine.symptom business |
| Zdroj: | Neurogastroenterology and motility, 14(6), 647-655. Wiley-Blackwell |
| ISSN: | 1350-1925 |
| Popis: | The aim of this study was to compare the effect of graded gastric barostat distension and meal-induced fundic relaxation on the elicitation of transient lower oesophageal sphincter relaxation (TLOSR). In 15 healthy subjects, stepwise fundic distension and oesophageal manometry were performed simultaneously. Next, the effect of meal ingestion on proximal stomach volume and lower oesophageal sphincter function was studied. During stepwise barostat distension of the proximal stomach, a significant linear correlation between intragastric pressure (r = 0.91; P |
| Databáze: | OpenAIRE |
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