Pervasive Mitonuclear Coadaptation Underlies Fast Development in Interpopulation Hybrids of a Marine Crustacean
| Autor: | Felipe S. Barreto, Kin Lan Han |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0106 biological sciences
AcademicSubjects/SCI01140 Male Nuclear gene copepods Population Biology 010603 evolutionary biology 01 natural sciences Genome pool-seq Copepoda Evolution Molecular 03 medical and health sciences Adenosine Triphosphate Gene Frequency postzygotic isolation Genetics Tigriopus californicus Animals Allele education hybridization Ecology Evolution Behavior and Systematics 030304 developmental biology Hybrid ATP synthesis Cell Nucleus 0303 health sciences education.field_of_study AcademicSubjects/SCI01130 Reproductive isolation Gene Pool biology.organism_classification Biological Evolution Mitochondria Evolutionary biology Genome Mitochondrial Hybridization Genetic Female Gene pool Genetic Fitness Sequence Analysis Research Article |
| Zdroj: | Genome Biology and Evolution |
| ISSN: | 1759-6653 |
| Popis: | Cellular energy production requires coordinated interactions between genetic components from the nuclear and mitochondrial genomes. This coordination results in coadaptation of interacting elements within populations. Interbreeding between divergent gene pools can disrupt coadapted loci and result in hybrid fitness breakdown. While specific incompatible loci have been detected in multiple eukaryotic taxa, the extent of the nuclear genome that is influenced by mitonuclear coadaptation is not clear in any species. Here, we used F2 hybrids between two divergent populations of the copepod Tigriopus californicus to examine mitonuclear coadaptation across the nuclear genome. Using developmental rate as a measure of fitness, we found that fast-developing copepods had higher ATP synthesis capacity than slow developers, suggesting variation in developmental rates is at least partly associated with mitochondrial dysfunction. Using Pool-seq, we detected strong biases for maternal alleles across 7 (of 12) chromosomes in both reciprocal crosses in high-fitness hybrids, whereas low-fitness hybrids showed shifts toward the paternal population. Comparison with previous results on a different hybrid cross revealed largely different patterns of strong mitonuclear coadaptation associated with developmental rate. Our findings suggest that functional coadaptation between interacting nuclear and mitochondrial components is reflected in strong polygenic effects on this life-history phenotype, and reveal that molecular coadaptation follows independent evolutionary trajectories among isolated populations. |
| Databáze: | OpenAIRE |
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