Contributing factors to mortality rates of pulmonary tuberculosis in intensive care units
| Autor: | Pinar Cimen, Dursun Tatar, Gunes Senol, Cenk Kirakli, Ozlem Edipoglu |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Tuberculosis medicine.medical_treatment 030106 microbiology law.invention 03 medical and health sciences Mechanical ventilation law Intensive care Humans Medicine Mortality Risk factor Tuberculosis Pulmonary Retrospective Studies lcsh:R5-920 APACHE II business.industry Mortality rate Medical record General Medicine Length of Stay Middle Aged medicine.disease Intensive care unit Intensive Care Units Emergency medicine Female lcsh:Medicine (General) business |
| Zdroj: | Journal of the Chinese Medical Association, Vol 81, Iss 7, Pp 605-610 (2018) |
| ISSN: | 1726-4901 |
| Popis: | Background Tuberculosis (TB) remains an important health problem worldwide. TB patients sometimes require intensive care unit (ICU) treatment. The aim of this study is to establish special features and mortality rates of pulmonary TB patients in ICUs and identify the factors contributing to ICU mortality. Methods Medical records of adult patients (>18 years) with a diagnosis of TB who were admitted to the ICU of a referral hospital for chest diseases between 2004 and 2010 were reviewed retrospectively. Demographic characteristics, comorbidities, APACHE II scores, symptoms, radiologic appearance of the disease, bacteriological and laboratory investigations, need and type of mechanical ventilation support (invasive, non-invasive), characteristics related to ICU stay, length of ICU stay, mortality and factors affecting mortality were recorded and analysed. Results Forty patients (33 male) with active pulmonary TB with a median age of 55 years (43–63 years) and a median APACHE II score of 22 (17–26) were followed up in the ICU. Patients who needed invasive mechanical ventilation had significantly longer ICU stays than patients who were treated with non-invasive ventilation or medical therapy (Log rank p = 0.014). Mortality was 72.5%. The only independent risk factor for mortality was having an APACHE II score ≥18. Conclusion The mortality of TB patients who needed ICU support remains high. This higher mortality rate seems related to multi-organ failure, requiring invasive mechanical ventilation and high APACHE II scores. |
| Databáze: | OpenAIRE |
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