Controlled microparticle manipulation employing low frequency alternating electric fields in an array of insulators
| Autor: | Blanca H. Lapizco-Encinas, Nadia M. Jesús-Pérez, Ana V. Chávez-Santoscoy, Javier L. Baylon-Cardiel |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Materials science
Time Factors Microfluidics Biomedical Engineering Bioengineering Insulator (electricity) Sawtooth wave Low frequency Biochemistry law.invention Electric Power Supplies Electromagnetic Fields law Electric field Computer Simulation Particle Size Microchannel Miniaturization business.industry Electrical engineering Reproducibility of Results General Chemistry Equipment Design Dielectrophoresis Models Theoretical Microspheres Kinetics Optoelectronics Alternating current business Algorithms Voltage Biotechnology |
| Zdroj: | Lab on a chip. 10(23) |
| ISSN: | 1473-0197 |
| Popis: | Low frequency alternating current insulator-based dielectrophoresis is a novel technique that allows for highly controlled manipulation of particles. By varying the shape of an AC voltage applied across a microchannel containing an array of insulating cylindrical structures it was possible to concentrate and immobilize microparticles in bands; and then, move the bands of particles to a different location. Mathematical modeling was performed to analyze the distribution of the electric field and electric field gradient as function of the shape of the AC applied potential, employing frequencies in the 0.2–1.25 Hz range. Three different signals were tested: sinusoidal, half sinusoidal and sawtooth. Experimental results demonstrated that this novel dielectrophoretic mode allows highly controlled particle manipulation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|