Impact of chronic use of heat-not-burn cigarettes on oxidative stress, endothelial dysfunction and platelet activation: the SUR-VAPES Chronic Study
Autor: | Isotta Chimenti, Roberta Marti, Cristina Nocella, Francesco Violi, Vittoria Cammisotto, Andrea Morelli, Elena De Falco, Antonino G.M. Marullo, Giuseppe Biondi-Zoccai, Mariangela Peruzzi, Sebastiano Sciarretta, Elena Cavarretta, Simona Battaglia, Roberto Carnevale, Lorenzo Loffredo, Stefano Pizzolo, Fabio Miraldi, Giacomo Frati, Simona Bartimoccia |
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Rok vydání: | 2020 |
Předmět: |
Pulmonary and Respiratory Medicine
Male Hot Temperature Heat not burn 030204 cardiovascular system & hematology Electronic Nicotine Delivery Systems medicine.disease_cause 03 medical and health sciences 0302 clinical medicine medicine Humans 030212 general & internal medicine Platelet activation Endothelial dysfunction Aged business.industry heated tobacco product oxidative stress tobacco control Vaping Smoking Tobacco Products Middle Aged medicine.disease Platelet Activation Oxidative Stress Immunology Female Endothelium Vascular business Oxidative stress |
Zdroj: | Thorax. 76(6) |
ISSN: | 1468-3296 |
Popis: | Tobacco habit still represents the leading preventable cause of morbidity and mortality worldwide. Heat-not-burn cigarettes (HNBCs) are considered as an alternative to traditional combustion cigarettes (TCCs) due to the lack of combustion and the absence of combustion-related specific toxicants. The aim of this observational study was to assess the effect of HNBC on endothelial function, oxidative stress and platelet activation in chronic adult TCC smokers and HNBC users. The results showed that both HNBC and TCC display an adverse phenotype in terms of endothelial function, oxidative stress and platelet activation. Future randomised studies are strongly warranted to confirm these data. |
Databáze: | OpenAIRE |
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