Kathon CG and Occupational Dermatology. An update

Autor: Jesús Rodríguez Espinosa, Ana Rita Rodrigues Barata, Felipe Heras Mendaza, Luis Conde-Salazar Gomèz
Přispěvatelé: [Rodrigues Barata,AR] Departamento de Dermatología y Venereología. Hospital Universitario Virgen Macarena. Sevilla, España. [Rodríguez Espinosa,J] Fraternidad Muprespa. Cuidad Real, España. [Heras Mendaza,F, Conde-Salazar Gomèz,L] Unidad de Dermatología Laboral. Instituto de Salud Carlos III. Pabellón 8 Universidad Complutense. Madrid, España.
Rok vydání: 2012
Předmět:
Isiothiazolines
Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Dermatitis::Dermatitis
Contact::Dermatitis
Allergic Contact [Medical Subject Headings]
Analytical
Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies::Retrospective Studies [Medical Subject Headings]
profesional
Cosmetics
Pintura
Chemicals and Drugs::Lipids::Oils [Medical Subject Headings]
Technology
Industry
Agriculture::Technology
Industry
and Agriculture::Manufactured Materials::Paint [Medical Subject Headings]
Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]
Estudios retrospectivos
cosméticos
Pruebas del parche
Registros médicos
Chemicals and Drugs::Pharmaceutical Preparations::Pharmaceutic Aids::Preservatives
Pharmaceutical [Medical Subject Headings]
Chemicals and Drugs::Organic Chemicals::Sulfur Compounds::Thiazoles [Medical Subject Headings]
Kathon CG
Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Dermatitis::Dermatitis
Contact::Dermatitis
Occupational [Medical Subject Headings]
Health Care::Population Characteristics::Socioeconomic Factors::Occupations [Medical Subject Headings]
Analytical
Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence [Medical Subject Headings]
Isotiazolinas
Ocupaciones
Diseases::Immune System Diseases::Hypersensitivity::Latex Hypersensitivity [Medical Subject Headings]
dermatitis de contacto
Contact dermatitis
Disciplines and Occupations::Health Occupations::Medicine::Dermatology [Medical Subject Headings]
Analytical
Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Records as Topic::Medical Records [Medical Subject Headings]
Occupational
Analytical
Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Immunologic Tests::Skin Tests::Patch Tests [Medical Subject Headings]
Chemicals and Drugs::Complex Mixtures::Colloids::Emulsions [Medical Subject Headings]
Conservadores farmacéuticos
Zdroj: Medicina y Seguridad del Trabajo v.58 n.228 2012
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
instname
Popis: espanolEl Kathon CG constituye el nombre comercial de una mezcla de isotiazolinas: Metilcloroisotiazolinona y Metilisotiazolinona. Es un conservante muy utilizado, sobre todo en la industria cosmetica, aunque en los ultimos anos tambien se ha impuesto su presencia en productos de limpieza de uso domestico y actualmente a concentraciones mas altas en preparados de uso industrial como aceites de corte, emulsiones de latex, pinturas al temple, aceites para motores Diesel, etc. Por su alto poder sensibilizante y amplia utilizacion, constituye actualmente una de las causas mas frecuentes de alergia de contacto por preservativos, tanto en nuestra vida privada, como en el ambito profesional. Objetivos: Estudiar la capacidad sensibilizante del Kathon CG y su relacion con el desarrollo de eczema de contacto alergico de origen profesional. Metodos: Estudio observacional descriptivo, a traves de la revision de las historias clinicas de los pacientes vistos en el Servicio de Dermatologia Laboral del Instituto Nacional de Medicina y Seguridad en el Trabajo durante los anos 2008-2012; 1520 pacientes fueron evaluados y estudiados mediante pruebas epicutaneas para descartar una posible dermatosis profesional. Se registraron los casos de sensibilizacion al Kathon CG y se analizaron las siguientes variables: genero, edad, grupo profesional, localizacion de las lesiones cutaneas, relevancia y relacion profesional. El analisis estadistico se realizo con el programa SPSS 15.0. Resultados: Se observo sensibilizacion al Kathon CG en 88 pacientes (5,8%), correspondiendo un 42% a sensibilizaciones de origen profesional. Conclusiones: La alergia de contacto profesional por Kathon CG constituye actualmente es un problema de alta prevalencia. Ante un paciente con positividad a este alergeno hay que interrogar siempre por su profesion. EnglishKathon CG is the tradename for a mixture of isothiazolines: methylchloroisothiazolinone and methylisothiazolinone. It is a widely used preservative, especially in the cosmetic industry, although in recent years is presence have also been imposed in cleaning products for household use and, at higher concentrations in industrial preparations such as cutting oils, latex emulsions, paints, oils for diesel engines, etc. Because of its high sensitizing power and widespread use, is currently one of the most common causes of allergic contact dermatitis, both in our private lives, as in the occupational field. Objectives: To study the sensitizing capacity of Kathon CG and its relation to the development of allergic contact dermatitis of occupational origin. Methods: We performed a retrospective study by reviewing the medical records of patients seen at the Department of Occupationsal Dermatology at the Instituto Nacional de Medicina y Seguridad en el Trabajo, during the years 2008-2012. In that period, 1520 patients were evaluated and studied by patch testing, to rule out an occupational skin condition. We recorded cases of sensitization to Kathon CG and analyzed the following data: gender, age, occupational group, location of skin lesions, relevance and occupational origin. Statistical analysis was performed using SPSS 15.0. Results: We observed sensitization to Kathon CG in 88 patients (5.8%), and 42% were of occupational origin. Conclusions: Occupational contact allergy to Kathon CG is currently a problem of high prevalence. In patients with sensitization to this allergen, we should always ask about their occupation.
Databáze: OpenAIRE
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