Diagnostic Value of FDG-PET/CT for the Identification of Extranodal Extension in Patients With Head and Neck Squamous Cell Carcinoma

Autor: Noriko Tsuda, Natsuo Oya, Yudai Kai, Ryo Toya, Takahiro Watakabe, Daizo Murakami, Tomohiko Matsuyama, Tetsuo Saito, Hidetaka Arimura, Hideki Nakayama, Shinya Shiraishi, Yorihisa Orita, Fumi Sakamoto, Ryoji Yoshida
Rok vydání: 2020
Předmět:
Zdroj: Anticancer Research. 40:2073-2077
ISSN: 1791-7530
0250-7005
DOI: 10.21873/anticanres.14165
Popis: BACKGROUND/AIM We evaluated the diagnostic value of functional imaging with [18F]-fluoro-2-deoxy-D-glucose (FDG)-positron emission tomography/computed tomography (PET/CT) for the identification of extranodal extension (ENE) in patients with head and neck squamous cell carcinoma (HNSCC). PATIENTS AND METHODS In this study, 94 patients with HNSCC who underwent FDG-PET/CT were enrolled. We recorded the maximum standardized uptake value (SUVmax), compared the results with pathologic findings, and evaluated the diagnostic performance of using a SUVmax cut-off value for ENE. RESULTS Of the 566 dissected levels examined, 53 (9.4%) exhibited ENE. The mean SUVmax of LN with and without ENE were 6.67 and 1.64, respectively (p
Databáze: OpenAIRE