Tumour Treating Fields (TTFields) promotes Rho kinase-dependent phosphorylation of the tight junction protein claudin-5

Autor: Salvador, E, Keßler, AF, Burek, M, Tempel Brami, C, Voloshin-Sela, T, Volodin, A, Adel, Z, Giladi, M, Ernestus, RI, Löhr, M, Förster, C, Hagemann, C
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: 73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCV145 /20220525/
DOI: 10.3205/22dgnc143
Popis: Objective: Tumor Treating Fields (TTFields) are alternating electrical fields that are approved and effective for glioblastoma therapy with a frequency of 200 kHz. At a frequency of 100 kHz, we have previously shown that TTFields can transiently open the blood-brain barrier (BBB) in vitro and in vivo [for full text, please go to the a.m. URL]
Databáze: OpenAIRE