Anosognosia for hemianaesthesia: a voxel-based lesion-symptom mapping study
| Autor: | Carlotta Fossataro, Dalila Burin, Anna Berti, Giulia Bellan, Alessandro Piedimonte, Francesca Garbarini, L Spinazzola, A Livelli, Lorenzo Pia |
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| Rok vydání: | 2013 |
| Předmět: |
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medicine.medical_specialty External capsule Cognitive Neuroscience somatosensory awareness Experimental and Cognitive Psychology Sensory system Audiology Neuropsychological Tests Insular cortex anosognosia for hemianaesthesia Lateralization of brain function Functional Laterality somatosensory expectancies Basal ganglia medicine Humans Anesthesia Aged anterior putamen Aged 80 and over Brain Mapping Sensory stimulation therapy Anosognosia Putamen Awareness Middle Aged medicine.disease Neuropsychology and Physiological Psychology Brain Injuries Agnosia Female Psychology Neuroscience |
| Zdroj: | Cortex; a journal devoted to the study of the nervous system and behavior. 61 |
| ISSN: | 1973-8102 |
| Popis: | Brain-damaged patients affected by hemianaesthesia (i.e., the loss of tactile sensibility on the contralesional side of the body) may deny their deficits (i.e., anosognosia for tactile deficits) even reporting tactile experience when stimuli are delivered on the impaired side. So far, descriptive analysis on small samples of patients reported that the insular cortex, the internal/external capsule, the basal ganglia and the periventricular white matter would subserve anosognosia for hemianaesthesia. Here, we aimed at examining in depth the anatomo-functional nature of anosognosia for hemianaesthesia by means of a voxelwise statistical analysis. We compared two groups of left hemiplegic patients due to right brain damages differing only for the presence/absence of anosognosia for left hemianaesthesia. Our findings showed a lesional cluster confined mainly to the anterior part of the putamen. According to the current anatomical evidence on the neural basis of sensory expectancies, we suggested that anosognosia for hemianaesthesia might be explained as a failure to detect the mismatch between expected and actual tactile stimulation. |
| Databáze: | OpenAIRE |
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