Dynamic contrast-enhanced and diffusion-weighted MR imaging in early prediction of pathologic response to neoadjuvant chemotherapy in locally advanced gastric cancer

Autor:	Jing Li, Liang-liang Yan, Hong-kai Zhang, Yi Wang, Shu-ning XU, Hai-liang Li, Jin-rong Qu
Rok vydání:	2022
Předmět:	Diffusion Magnetic Resonance Imaging Radiological and Ultrasound Technology Stomach Neoplasms Urology Gastroenterology Contrast Media Humans Radiology Nuclear Medicine and imaging Magnetic Resonance Imaging Neoadjuvant Therapy
Zdroj:	Abdominal radiology (New York). 47(10)
ISSN:	2366-0058
Popis:	To investigate the efficacy of diffusion-weighted imaging (DWI) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for the early prediction of the pathologic response to neoadjuvant chemotherapy (NAC) in patients with locally advanced gastric cancer (LAGC).Fifty patients with LAGC who were treated with NAC followed by radical gastrectomy were enrolled. Uncontrasted and DCE-MRI were performed within 1 week before NAC. According to tumor regression grading (TRG), patients were labeled as responders (TRG = 0 + 1) and non-responders (TRG = 2 + 3). Apparent diffusion coefficients (ADC) and DCE-MRI kinetics (KADC, KBoth DWI and DCE-MRI can effectively predict the pathologic response to NAC in LAGC. A combination of ADC and K
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8408a4a538c4bce476bed7c57a6f3233 https://pubmed.ncbi.nlm.nih.gov/35916943 Zobrazit plný text záznamu Full text from SpringerLink