Inhibition of plasminogen activators and the growth of cultured human tumour cells
| Autor: | G.Kenneth Scott |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Cell type
Cell growth Chemistry Cell Antibodies Monoclonal Urokinase-Type Plasminogen Activator Biochemistry Molecular biology Plasminogen Activators Plasminogen Inactivators Specific antibody medicine.anatomical_structure Tissue Plasminogen Activator alpha 1-Antitrypsin Tumor Cells Cultured medicine Humans Fibroblast Cell Division HeLa Cells |
| Zdroj: | International Journal of Biochemistry. 20:817-822 |
| ISSN: | 0020-711X |
| Popis: | 1. 1. Inhibition of a human fibroblast cell-surface proteinase with α-1-antitrypsin also inhibited cell proliferation, confirming earlier observations. 2. 2. Although a similar proteinase inhibition could be observed with human tumour cells, the growth of these cells was unaffected. 3. 3. Plasminogen activators on the cell surface and in culture media could be inhibited with specific antibodies, but there was no corresponding effect on the growth of any of the cell types tested. |
| Databáze: | OpenAIRE |
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