Production of extracellular trypsin and chymotrypsin inhibitors by aStreptomyces sp
| Autor: | Valya Peretz, B. Angelova, Yordanka Kourteva |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
chemistry.chemical_classification
Chymotrypsin biology Nitrogen Starch General Medicine Trypsin biology.organism_classification Applied Microbiology and Biotechnology Streptomyces Carbon Culture Media chemistry.chemical_compound chemistry Biochemistry Biosynthesis Tryptone Extracellular biology.protein medicine Monosaccharide Trypsin Inhibitors medicine.drug |
| Zdroj: | Journal of Basic Microbiology. 29:413-417 |
| ISSN: | 1521-4028 0233-111X |
| DOI: | 10.1002/jobm.3620290704 |
| Popis: | The production of extracellular inhibitors by Streptomyces sp. 1-72, specific either to trypsin (TI-1), or to chymotrypsin (CI-1), was investigated in relation to the cell growth and composition of the cultivation media. The biosynthesis of the inhibitors was found to be of a growth-associated type which reached a maximum level at late exponential phase. All of the investigated carbon sources, including starch, disaccharides and monosaccharides, equally supported the production of both inhibitors, while the effect of the different nitrogen sources considerably varied, some of them being totally ineffective. The sources which mostly supported the biosynthesis of the inhibitors were tryptone (3%) for TI-1, and peptone (3%) for CI-1 respectively. |
| Databáze: | OpenAIRE |
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