Neuroanatomic Localization of Magnetic Resonance Imaging Signal Hyperintensities in Geriatric Depression
| Autor: | Charles Auerbach, K. Ranga Rama Krishnan, Elisse Kramer-Ginsberg, Manzar Ashtari, Mahendra Patel, Blaine S. Greenwald |
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| Rok vydání: | 1998 |
| Předmět: |
Male
medicine.medical_specialty Functional Laterality White matter Internal medicine medicine Humans Psychiatry Depression (differential diagnoses) Aged Advanced and Specialized Nursing Brain Mapping medicine.diagnostic_test Depression business.industry Leukoaraiosis Magnetic resonance imaging Magnetic Resonance Imaging Hyperintensity medicine.anatomical_structure Hypertension Cardiology Female Neurology (clinical) Cardiology and Cardiovascular Medicine business |
| Zdroj: | Stroke. 29:613-617 |
| ISSN: | 1524-4628 0039-2499 |
| DOI: | 10.1161/01.str.29.3.613 |
| Popis: | Background and Purpose —Increased frequency and severity of signal hyperintensities have been regularly reported in elderly depressed patients compared with normal subjects, however, greater neuroanatomic localization of lesions has been limited. Methods —T2-weighted MRI scans in elderly depressed patients (n=35) and normal comparison subjects (n=31) were assessed for signal hyperintensities in lateralized discrete brain regions. Results —Logistic regression revealed that left frontal deep white matter ( P P Conclusions —Findings suggest that greater neuroanatomic localization of hyperintensities than heretofore appreciated may relate to late-life depression. |
| Databáze: | OpenAIRE |
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