Clinical management and acute exacerbations in patients with idiopathic pulmonary fibrosis in Spain: results from the OASIS study

Autor: Esteban Cano-Jiménez, Ana Dolores Romero Ortiz, Ana Villar, María Jesús Rodríguez-Nieto, Alba Ramon, Silvia Armengol
Přispěvatelé: Institut Català de la Salut, [Cano-Jiménez E] Servicio de Neumología, ILD Unit, Hospital Universitario Lucus Augusti, C/ Ulises Romero N 1, 27003 Lugo, Spain. [Romero Ortiz AD] Servicio de Neumología, Hospital Universitario Virgen de Las Nieves, Granada, Spain. [Villar A] Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Rodríguez-Nieto MJ] Servicio de Neumología, IIS Fundación Jiménez Diaz, CIBERES, Madrid, Spain. [Ramon A, Armengol S] Boehringer Ingelheim España, Sant Cugat del Vallès, Spain, Vall d'Hebron Barcelona Hospital Campus
Rok vydání: 2022
Předmět:
Health Services Administration::Patient Care Management::Disease Management [HEALTH CARE]
Fibrosi pulmonar - Tractament
Idiopathic pulmonary fibrosis (IPF)
Clinical management
administración de los servicios de salud::gestión de la atención al paciente::tratamiento de las enfermedades [ATENCIÓN DE SALUD]
Fibrosi pulmonar - Prognosi
Otros calificadores::/diagnóstico [Otros calificadores]
Idiopathic Pulmonary Fibrosis
IPF management
IPF acute exacerbations
Environment and Public Health::Public Health::Epidemiologic Measurements::Demography::Health Status::Quality of Life [HEALTH CARE]
Spain
Early treatment
Avaluació de resultats (Assistència sanitària)
Other subheadings::/diagnosis [Other subheadings]
Quality of Life
Humans
Respiratory Tract Diseases::Lung Diseases::Lung Diseases
Interstitial::Idiopathic Interstitial Pneumonias::Idiopathic Pulmonary Fibrosis [DISEASES]
enfermedades respiratorias::enfermedades pulmonares::enfermedades pulmonares intersticiales::neumonías intersticiales idiopáticas::fibrosis pulmonar idiopática [ENFERMEDADES]
Prospective Studies
IPF progression
ambiente y salud pública::salud pública::medidas epidemiológicas::demografía::estado de salud::calidad de vida [ATENCIÓN DE SALUD]
Zdroj: Scientia
ISSN: 1465-993X
Popis: Background Idiopathic pulmonary fibrosis (IPF) is a progressive disease associated with decline in lung function and poor prognosis entailing significant impairment in quality of life and high socioeconomic burden. The aim of this study was to characterize clinical management and resources utilization of patients with IPF in Spain, according to predicted forced vital capacity (FVC) % at baseline. Methods Prospective, non-interventional, multicentric real-world data study in patients with IPF in Spain with 12-months follow-up. Clinical management and resources utilization during study period were recorded and compared between groups. FVC decline and acute exacerbations occurrence and associated healthcare resource use were also analysed. FVC decline after 12 months was estimated as relative change. Results 204 consecutive patients with IPF were included and divided according to baseline FVC % predicted value. At baseline, patients with FVC 10% in the more preserved lung function groups than in the FVC Conclusions We observed a significantly higher annual IPF-related resource use in patients with more impaired lung function at baseline. Since FVC decreases irrespective of FVC% predicted at baseline, slowing IPF progression to maintain patients at early disease stages is relevant to improve IPF management and to optimize resource use. Trial registration: EU PAS register number EUPAS19387 [June 01, 2017].
Databáze: OpenAIRE
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